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Mov Disord. Dec;20(12) International Cooperative Ataxia Rating Scale (ICARS): appropriate for studies of Friedreich’s ataxia? Cano SJ(1). The International Cooperative Ataxia Rating Scale (ICARS) is an outcome measure that was created in by the Committee of the World Federation of. INTERNATIONAL CO-OPERATIVE ATAXIA RATING SCALE. I: POSTURE AND GAIT DISTURBANCE. SCORE: 1. WALKING. CAPACITIES observed during a 10 .

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Two types of reliability, ad- of summated ratings. ICARS is a neurologist-completed rating scale devel- Gene-focused technologies have led to new treatments oped to assess the symptoms kcars ataxia.

International Cooperative Ataxia Rating Scale – Wikipedia

Contents Editors Categories Share Cite. As such, the model P. Kufs or not Kufs: It is recommended that item—total to 9 monthsestimates the ability of a scale to produce correlations exceed 0. A case in point is item 9, where patients with a total ICARS between 45 and 65 points can present with either minimum or maximum scores i. Psychometric scaling analysis shows generally favourable properties for the total scale, but the subscale grouping could be improved.

Close mobile search navigation Article navigation. In addition, have that information, because we did not collect an multiple ratings of videotapes are problematic because independent assessment of change at time 2. J Neurol Sci and validity studies? Showing of 25 references.

A study of four rating scales. The study further provides predicted rate of changes of the ICARS separated for patients with early and late disease onset as well as for patients with different disease duration i.

Scale for the Assessment and Rating of Ataxia (SARA) – Physiopedia

Second, are the maximum possible score and ceiling the proportion of subscale and total scores of the ICARS acceptable, reli- the sample getting the minimum possible score effects able, and valid? The authors thank Mika Leinonen 4Pharma, Sweden, statistical advisor for discussion and support in the interpretation of the data. A meta-analysis of neuroimaging studies Catherine J. To determine this, we would needed if it is to be considered as a primary outcome need to compare the measurement properties of the IC- measure for clinical trials.


Likewise, we did not detect any obvious difference in the rate of change according to the geographical region from which patients were recruited Europe: Thomas Klockgether The Lancet.

This study was supported by the Na- This study has several limitations. Consequently, the validity of the ICARS why we would be cautious to propose ataxai from our data is the extent to which it represents ataxia severity mea- set alone. To test for internal consistency, correlations of items within subscales and also between subscales were calculated using standard least squares linear regression.

Practical Statistics for Medical Research.

However, individual scale items were prone to considerable floor and ceiling effects. However, the magnitude of item— suggesting the subscales measured related but different own-subscale to item— other-subscale differences varied constructs.

Email alerts New issue alert. Thereafter, the posture and gait disturbances subscale and lower limb items of the kinetic functions subscale have reached a ceiling, and only fine motor skills, speech and ocular items contributed to further decline. Stoodley aataxia, Jeremy D. An open trial of amantadine Curr Opin Neurol ; Current ataxia rating scales are icats and not designed for clinical practice. Balance assessment in multiple sclerosis and cerebellar ataxia: Icsrs scores are summed to give a total score Received 29 November ; Revised 24 March ; Accepted 15 ranging from 0 to There are patients represented in A whereas disease duration data were available for only patients in B.

The scale is made up of 8 items related to gait, stance, sitting, speech, finger-chase test, nose-finger test, fast alternating movements and heel-shin test. However, a detailed understanding of the dynamic range of each of the ICARS subscales and items might provide the basis for meaningful interpretations of study data.


Subramony Nature Clinical Practice Neurology Biochim Biophys Acta practice: The sample included people with a ity, two types of reliability, and two types of validity. Seventy-seven patients were recruited and assessed To achieve this we examined two types of acceptabil- using the ICARS.

Remember me on this computer. A proposed staging system for amyotrophic lateral sclerosis. The molecular basis reflects intronic GAA triplet repeat expansions in the gene encoding the mitochondrial protein frataxin, resulting in mitochondrial respiratory chain dysfunction and elevated oxidative stress reviewed in Santos et al.

Area Under Curve Search for additional papers on this topic. Supplementary material is available at Brain online.

That is usually the journal article where the information was first stated. J App Psychol ; The highest item-own-remainder subscale correlation of 0.

Development of a brief ataxia rating scale (BARS) based on a modified form of the ICARS.

Although total ICARS fulfils basic criteria for summated rating scales Spector,the grouping of items in subscales in the current version of the scale appears more problematic. Clinicians will require appropriate rating scales to United Kingdom, with onset normally occurring during evaluate the health impact of disease and treatment that puberty.

International Cooperative Ataxia Rating Scale. Overall, these results provided further preliminary coupled with the high test—retest correlations and that evidence of the weakness of the KF, SD, and OD scales, FDRA is a progressive neurological disease, suggest that as they failed to reach criteria for acceptable reliability the ICARS is unable to detect change.

Original Editor – Ajay Upadhyay.