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Resumen. DELGADO FERNANDEZ, María del Rosario; ROMERO RIVERO, Oscar Luis y DIAZ BORROTO, Abel. Central insipid diabetes: presentation of a case. Articulo en XML; Referencias del artículo; Como citar este artículo; SciELO Analytics; Enviar Neurohypophisis and Insipid Diabetes: A description of a case. Palabras clave: Neurohipófisis [Histología]; Diabetes Insípida [ Diagnóstico];. Existen dos tipos: diabetes insípida (DI) central, debida a la síntesis o liberación defectuosas de arginina vasopresina (AVP) desde el Artículos de referencia.

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BMJ Best Practice

Clin Neurosurg ; Its synthesis is accompanied by the generation of a specific aritculos protein called neurophysin II. Show more Show less. This results in water reabsorption in the collecting duct of the nephron following an osmotic gradient. The foregoing precludes progressive weight loss. Inadequately low levels for plasma osmolality have also been demonstrated in patients with neurogenic diabetes insipidus and high levels of vasopressin in those with nephrogenic diabetes insipidus.

Insipid there is sufficient evidence to continue treatment with hydrochlorothiazide and amiloride 0.

Transsphenoidal neurosurgery of intracranial neoplasm. The most important biological action atticulos AVP is preservation of body water by reducing urinary output.

In our experience, despite tumor extension to the cavernous sinus, pituitary macroadenomas can be safely resected with low morbidity and mortality. In the former, the patient generally, because of psychological disorders, ingests large quantities of water and other fluids, which causes a compensatory polyuria and a clinical picture similar to diabetes insipidus is seen, but without completely affecting the power of renal concentration.


A tenor de estos hallazgos, Knosp et al. Acquired nephrogenic diabetes insipidus can be caused by electrolyte imbalances e.

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Other manifestations include constipation, nicturia and noctural enuresis in older children. You can change the settings or obtain more information by clicking here. Weight and urinary volume should be controlled each hour; if polyuria is great, weight control should be done every 30 min.

The latter in turns activates protein kinase A, which phosphorylates the preformed aquaporin-2 water channel located in the intracellular vesicles. Sheehan’s syndrome refers to the occurrence of hypopituitarism after delivery, usually preceded by postpartum hemorrhage. The process of secretion requires calcium entry through the membrane. Diabetes insipidus is a disease characterized by the elimination of high volumes of very dilute urine.

Variations on the insipid transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: The secondary form is what is observed as part of the clinical picture of different nephropathies Table djabetes Pathology of invasive pituitary tumors with special reference to functional classification.

Diabetes insípida central: presentación de un caso

To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. There is no specific treatment when we are dealing with a primary disorder. A similar alteration in the functioning of the renal tubule has been seen in patients with hypercalcemia who develop the picture of nephrogenic diabetes insipidus.

We describe the clinical course of a young lady who after her sixth childbirth developed severe riabetes hemorrhage followed by development of panhypopituitarism which was confirmed by hormonal investigation and demonstration of empty sella on imaging. The fluid deprivation test should be performed in young children with significant polyuria and diabdtes diagnosis of primary neurogenic or nephrogenic diabetes insipidus, under strict vigilance so as to avoid a severe picture of dehydration.


We will respond to all feedback. Expression of phosphorylated p27 Kip1 protein and Jun activation domain-binding protein 1 in human pituitary tumors.

The journal publishes the following articles types: For any urgent enquiries please contact our customer services team who are ready to help with any problems. Congenital nephrogenic diabetes insipidus is a disorder associated with mutations in either the AVPR2 or AQP2 gene, causing the inability of patients to concentrate their urine. Please enter a valid username and password and try again. Sheehan’s syndrome; central diabetes insipidus; water deprivation test.

Sin embargo, la morbilidad no es despreciable 5, Se continuar a navegar, consideramos que aceita o seu uso. En el seguimiento de los pacientes con restos tumorales en la RM de artculos preferimos adoptar una actitud conservadora. SRJ is a prestige metric based on the idea that not all citations are the same.

Twenty three operations were performed on twenty-two patients. Can J Neurol Sci ; This test is very useful to establish the diagnosis of diabetes insipidus of any etiology and to differentiate from compulsive polydipsia or potomania. With these urine samples the osmolality and density and the amount of urine will be determined.